As a polygenicdisorder, genetic studies have only started to shed light on its complex etiology.
2
The data provide strong evidence for the model of Crohn's disease and ulcerative colitis as related polygenicdisorders.
3
Systematic screening of the entire human genome now provides a strategy for the identification of susceptibility genes in complex polygenicdisorders.
4
Neuropsychiatric disorders are highly heritable polygenicdisorders arising from the complex interplay of highly penetrant rare variants and common variants of small effect.
Uso de polygenic disease en inglés
1
Osteoporosis is a polygenicdisease, whose determining loci have not yet been identified.
2
Human essential hypertension is a polygenicdisease whose phenotypic expression is modulated by the environment.
3
Osteoporosis is a common polygenicdisease and global healthcare priority but its genetic basis remains largely unknown.
4
Genetic studies in patients and mouse models have shown that alopecia areata is a complex, polygenicdisease.
5
Essential hypertension is a complex, polygenicdisease derived from the interaction of patient's genetic background with the environment.
6
Consanguinity increases risk for numerous monogenic and polygenicdiseases.
7
Nutritional genomics aims to prevent, treat, and manage polygenicdiseases through targeted therapies formulated from individuals' genetic makeup and dietary intake.
8
If validated, GMAS may imply that common polygenicdiseases are related as much to group interactions between normal genes, as to multiple gene mutations.